Does TracePharma translate EDI 850/856 into EPCIS?

TracePharma is EPCIS-native. ASNs and EDI documents can supplement receiving workflow, but DSCSA serial accountability requires EPCIS ingest. We match ASN data to EPCIS when both are present—not replace EPCIS with EDI alone.

Do I need Axway or another EDI vendor?

Only when partners or IT require a gateway. TracePharma supports direct AS2 and SFTP without middleware for many mid-market deployments.

Integrations / AS2 & EDI

Integrations · AS2 & EDI

EPCIS over AS2, SFTP, and EDI middleware

DSCSA accountability travels as EPCIS—not generic EDI 850 purchase orders. TracePharma receives signed AS2 messages, polls SFTP inboxes, and accepts HTTPS webhooks from Axway and other B2B gateways.

Axway integration → Request a demo →

Buyers often ask for “EDI integration.” In DSCSA programs, the critical payload is EPCIS (serial-level custody events). It is often delivered via AS2 with signed MDN—not ASN X12 alone. TracePharma ingests EPCIS through native AS2, SFTP polling, and HTTPS capture.

Warehouse ASNs (EDI 856) remain useful for dock workflow; TracePharma matches them to EPCIS where both arrive. See the EPCIS vs ASN guide for the distinction.

Native AS2

✓ Inbound AS2 receive with partner certificate registration.
✓ Signed MDN handling and ACK tracking in integration health.
✓ Used by McKesson AS2 preset, TraceLink partners, and custom manufacturer connections.

SFTP polling

✓ Scheduled poll of wholesaler and partner SFTP inboxes.
✓ Cardinal and Cencora presets ship with path and format hints.
✓ Processed-file archival and exception surfacing on failed parses.

EDI / B2B middleware

✓ Axway and similar gateways forward EPCIS to TracePharma HTTPS or AS2 endpoints.
✓ Enterprise EDI teams keep existing partner profiles; TracePharma is the L4 application layer.
✓ See Axway interoperability page for gateway cutover checklist.

HTTPS & REST

✓ McKesson HTTPS JSON, LSPedia webhooks, Gateway Checker push.
✓ POST /api/v1/epcis/capture for partner REST delivery.
✓ Outbound webhooks for downstream ERP/WMS automation.

Related integration pages

AS2, EDI & EPCIS FAQ

Does TracePharma translate EDI 850/856 into EPCIS?: TracePharma is EPCIS-native. ASNs and EDI documents can supplement receiving workflow, but DSCSA serial accountability requires EPCIS ingest. We match ASN data to EPCIS when both are present—not replace EPCIS with EDI alone.
Do I need Axway or another EDI vendor?: Only when partners or IT require a gateway. TracePharma supports direct AS2 and SFTP without middleware for many mid-market deployments.

Mapping AS2 certificates or SFTP paths?

Bring your partner spec—we'll configure inbound connections and test receiving on a demo tenant.

Request a demo